BDBM17446 (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl N-(2-chloroacetyl)carbamate::CHEMBL424278::TNP-470
SMILES [H][C@@]1([#6@H](-[#8]-[#6])-[#6@@H](-[#6]-[#6][C@]11[#6]-[#8]1)-[#8]-[#6](=O)-[#7]-[#6](=O)-[#6]Cl)[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6]
InChI Key InChIKey=MSHZHSPISPJWHW-PVDLLORBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 17446
Affinity DataKi: 1nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of MetAP2 after 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of MetAP2 (unknown origin) after 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair